Antibiotic Prophylaxis For Cesarean Section

Studies have investigated effectiveness choice of drug timing duration and appropriate route of administration.
Antibiotic prophylaxis for cesarean section. In patients with known mrsa colonization undergoing cesarean consideration may be given to adding a single dose of vancomycin to the recommended antibiotic prophylaxis regimen. Several controversies exist regarding the use of antibiotic prophylaxis in cesarean section. Approximately 4 million babies are born each year in the united states.
Timing 60 min before incision re dose surgery more than 4 hours blood loss greater than 1500 ml allergy clindamycin 900 mg gentamycin 5 mg kg multi dose no. Efficacy of antibiotic prophylaxis in preventing postoperative endometritis in certain high risk. 1 department of pathology and molecular medicine faculty of health sciences mcmaster university room 2n16 1200 main street west hamilton ontario canada l8n 3z5.
Latency antibiotics are recommended. Compared with placebo or no treatment the use of prophylactic antibiotics in women undergoing cesarean section reduced the incidence of wound infection rr 0 40 95 ci 0 35 to 0 46 82 studies 14 407 women endometritis rr 0 38 95 ci 0 34 to 0 42 83 studies 13 548 women and maternal serious infectious complications rr 0 31 95 ci 0 20 to 0 49 32 studies 6159 women. Cefazolin 1 g iv for patients 80 kg.
Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Smaill fm 1 gyte gm. For antibiotic prophylaxis for caesarean section a single dose of first generation cephalosporin or penicillin should be used in preference to other classes of antibiotics.
Eunice kennedy shriver nichd mfmu network trial regimen. One of the many concerns about cesarean deliveries is the. Very low quality evidence conditional recommendation.
The gdg noted that it is essential for clinicians to be clear about this description to avoid using antibiotic regimens that are most applicable for treating confirmed infection i e. We evaluated the benefits and safety. Standard antibiotic prophylaxis for cs.